The Organization of Teratology Information Specialists (OTIS) is the professional scientific society made up of the experts that provide the MotherToBaby service, and the researchers that perform the MotherToBaby pregnancy studies. OTIS was established in 1987 as a way of connecting world-renowned experts in the field of birth defects research to the general public. OTIS was incorporated in April 1999 as a nonprofit organization. In 2002 OTIS established a national call routing system so that anyone in North America calling the toll-free number, 1-866-626-6847, would be routed to an affiliated service to speak with an expert.
In 2013, OTIS announced MotherToBaby, a name for its public-facing service and research studies. Today, MotherToBaby affiliates around the world provide the most cutting-edge and up-to-date information about the risks of medications, chemicals, herbal products, illicit drugs, diseases and much more during pregnancy and while breastfeeding. OTIS and its information service, MotherToBaby, are suggested resources by many agencies including the Centers for Disease Control and Prevention (CDC). More than 100,000 women and their health care providers seek information about birth defect prevention from OTIS and MotherToBaby every year.